Increased cerebrospinal fluid biomarkers of angiogenesis in Parkinson’s disease.

20 July, 2015

Objective: To study biomarkers of angiogenesis in Parkinson’s disease (PD), and how these are associated with clinical characteristics, blood-brain barrier (BBB) permeability, and cerebrovascular disease. Methods: Thirty-eight elderly controls and 100 PD patients (82 without dementia and 18 with dementia) were included from the prospective Swedish BioFinder study. Cerebrospinal fluid (CSF) samples were analyzed for the

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Comparison of Amyloid PET and CSF Biomarkers for Identifying Early Alzheimer’s Disease

Objective To compare the diagnostic accuracy of cerebrospinal fluid (CSF) biomarkers and amyloid PET for diagnosing early-stage Alzheimer’s disease (AD). Methods From the BioFINDER study, we included 122 healthy elderly and 34 patients with mild cognitive impairment who developed AD dementia within 3 years (MCI-AD). Amyloid-β (Aβ) in 8 brain regions and globally was examined

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