News articles
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Revolutionary diagnostic blood test for Alzheimer’s
Wallenberg Clinical Scholar Oskar Hansson has researched Alzheimer’s disease for just over twenty years. He has developed a number... Read more... -
Research into methods for diagnosing Alzheimer’s receives SEK 10 million from the Torsten Söderberg Foundation
Finding a safe and simple way to diagnose Alzheimer’s disease in primary healthcare has long been a dream. This... Read more... -
New blood marker can identify Parkinsonian diseases
Is it possible that a single biomarker can detect all types of diseases related to dopamine deficiency in the... Read more... -
Lewy body disease can be detected before symptoms
Lewy body disease is the second most common neurodegenerative disease after Alzheimer’s disease. A research group from Lund University... Read more... -
ERC Advanced Grant for Alzheimer’s Research
Three researchers at Lund University in Sweden, all with a long list of significant research credentials, have been awarded... Read more... -
Triple success in prestigious EU grant round
Three researchers at Lund University in Sweden, all with a long list of significant research credentials, have been awarded... Read more...
Recent key publications
Revised criteria for the diagnosis and staging of Alzheimer’s disease
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology
Tau Positron Emission Tomography for Predicting Dementia in Individuals With Mild Cognitive Impairment
Disease staging of Alzheimer’s disease using a CSF-based biomarker model
A blood-based biomarker workflow for optimal tau-PET referral in memory clinic settings
Highly Accurate Blood Test for Alzheimer’s Disease Comparable or Superior to Clinical CSF Tests.
Plasma Biomarker Strategy for Selecting Patients With Alzheimer Disease for Antiamyloid Immunotherapies.
The α-synuclein PET tracer [18F] ACI-12589 distinguishes multiple system atrophy from other neurodegenerative diseases.
DOPA decarboxylase is an emerging biomarker for Parkinsonian disorders including preclinical Lewy body disease.
Cognitive effects of Lewy body pathology in clinically unimpaired individuals.
Clinical effects of Lewy body pathology in cognitively impaired individuals.
CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease.
X posts
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Here is a clinical perspective on the revised criteria and staging of Alzheimer’s disease.
The proposal is in many ways similar to how my Memory Clinic in Malmö (Sweden) has been using CSF AD biomarkers since 1998.
https://rdcu.be/dNOMf
🚨New preprint!
We’re happy to share our newest work “A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker tests”, 🩸led by the talented PhD student @ncjwarmenhoven 👇🏽
https://www.medrxiv.org/content/10.1101/2024.07.02.24309629v1
8⃣ Take home message:
Based on the recent Global CEO recommendations for plasma markers, plasma %p-tau217 can be a standalone confirmatory test for AD, while immunoassays may be used as preliminary tests needing confirmation
9⃣We would like to thank the BioFINDER team, our collaborators, the @WUADRC team, and co-authors @gesalbla, @DivyaBali06, @A_OrdunaDolado , @SuzanneESchind1, @alexa_pichetb @NicholasAshton, @OskarHansson9, and those without X!
And of course, all study participants! 🙌🏽
Donanemab received traditional approval by FDA today.
Personally I am very eager to see the results from the Trailblazer-Alz3 trial. Will we see larger effects when treatment is initiated during the preclinical disease stages?
🚨New paper out led by PhD Student @A_OrdunaDolado ‼️
"Effect of time of the day at sampling on CSF and plasma levels of Alzheimer’s Disease biomarkers” now on @AlzheimersRes!
https://alzres.biomedcentral.com/articles/10.1186/s13195-024-01503-x
8⃣ This work highlights the need to consider circadian effects on potential AD biomarkers⏲️🔄.
9⃣Huge thanks to all co-authors! @EStomrud, @NicholasAshton, Johanna Nilsson, @wagnersbrum, all collaborators at Roche, Ann Brinkmalm, Kaj Blennow, Henrik Zetterberg, Shorena Janelidze & @OskarHansson9.