Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity.

25 August, 2017

Abstract It is not known exactly where amyloid-β (Aβ) fibrils begin to accumulate in individuals with Alzheimer’s disease (AD). Recently, we showed that abnormal levels of Aβ42 in cerebrospinal fluid (CSF) can be detected before abnormal amyloid can be detected using PET in individuals with preclinical AD. Using these approaches, here we identify the earliest

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Performance of Different Amyloid Immunoassays in Predicting Outcome of Visual Assessment of Amyloid PET Imaging

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Cerebral hypoperfusion is not associated with an increase in amyloid β pathology in middle-aged or elderly people.

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Distinct 18F-AV-1451 tau PET retention patterns in early- and late-onset Alzheimer’s disease

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18F-AV-1451 and CSF T-tau and P-tau as biomarkers in Alzheimer’s disease.

9 August, 2017

18F-AV-1451 and CSF T-tau and P-tau as biomarkers in Alzheimer’s disease.

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