News articles
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How dementia affects the brain’s ability to empathize
Patients with frontotemporal dementia often lack the ability to feel empathy. A study at Lund University and the Karolinska... Read more... -
Reading the signs of dementia
In this Nature outlook the BioFINDER study group’s work on how blood tests are leading to earlier diagnosis, and... Read more... -
Key Milestones in Alzheimer’s Disease Research
In the article “The History of Alzheimer’s Disease”, the editors of Nature journals share their insights on this topic.... Read more... -
Groundbreaking Alzheimer’s blood test proves highly effective in primary healthcare
A commercially available blood test has now been trialled in routine healthcare. “The blood test showed about 90% reliability... Read more... -
Revolutionary diagnostic blood test for Alzheimer’s
Wallenberg Clinical Scholar Oskar Hansson has researched Alzheimer’s disease for just over twenty years. He has developed a number... Read more... -
Research into methods for diagnosing Alzheimer’s receives SEK 10 million from the Torsten Söderberg Foundation
Finding a safe and simple way to diagnose Alzheimer’s disease in primary healthcare has long been a dream. This... Read more...
Recent key publications
Alpha-synuclein seed amplification assay longitudinal outcomes in Lewy body disease spectrum.
Altered Empathy Processing in Frontotemporal Dementia.
Diagnosis of Alzheimer’s disease using plasma biomarkers adjusted to clinical probability.
A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker tests.
Lewy body pathology exacerbates brain hypometabolism and cognitive decline in Alzheimer’s disease.
Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care
Plasma Phosphorylated Tau 217 and Aβ42/40 to Predict Early Brain Aβ Accumulation in People Without Cognitive Impairment
MRI Signature of α-Synuclein Pathology in Asymptomatic Stages and a Memory Clinic Population
Revised criteria for the diagnosis and staging of Alzheimer’s disease
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology
Tau Positron Emission Tomography for Predicting Dementia in Individuals With Mild Cognitive Impairment
Disease staging of Alzheimer’s disease using a CSF-based biomarker model
A blood-based biomarker workflow for optimal tau-PET referral in memory clinic settings
Highly Accurate Blood Test for Alzheimer’s Disease Comparable or Superior to Clinical CSF Tests.
Plasma Biomarker Strategy for Selecting Patients With Alzheimer Disease for Antiamyloid Immunotherapies.
The α-synuclein PET tracer [18F] ACI-12589 distinguishes multiple system atrophy from other neurodegenerative diseases.
DOPA decarboxylase is an emerging biomarker for Parkinsonian disorders including preclinical Lewy body disease.
Cognitive effects of Lewy body pathology in clinically unimpaired individuals.
Clinical effects of Lewy body pathology in cognitively impaired individuals.
CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease.
X posts
I was very grateful to meet the former Swedish prime minister Ingvar Carlsson today. He told about his experiences in taking care of his wife with Alzheimer’s disease for the last decade. He is such a fantastic and kind person! And still going strong when 90 years old.
Which p-tau 217 assay for Alzheimer's was the best in comparative testing? This question is becoming an increasingly important one, as p-tau 217 has emerged as a possible single test which has great value. Noëlle Warmenhoven shares results in a fresh collaborative @Brain1878…
This head-to-head-comparison of key plasma p-tau217 biomarker tests by @ncjwarmenhoven is now published in @Brain1878 ! 🧠
https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awae346/7848519
Some additional, interesting details👇
Take home message:
Based on the recent Global CEO recommendations for plasma markers, plasma %p-tau217 can be a standalone confirmatory test for AD, while immunoassays may be used as preliminary tests needing confirmation.
Big thanks again to all co-authors, the BioFINDER team, collaborators, the @WUADRC team, and all study participants! 🎉
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Grant Manager in the Swedish BioFINDER study group
Description of the workplace Join the cutting-edge of neurodegeneration research with the world-renowned BioFINDER team ...
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