Population & Study Design

Overview

Overview

Memory Clinic Cohort

ENROLLMENT

Patients with cognitive symptoms at the memory clinic, Skåne University Hospital, that undergo lumbar puncture as part of their cognitive evaluation are consecutively recruited to the study until 1200 participants are reached.

INCLUSION CRITERIA

  • Under investigation for cognitive symptoms at the Memory clinic.
  • Cerebrospinal fluid and blood sampling is planned to be done as part of clinical practice even if the patient is not taking part of this study.

EXCLUSION CRITERIA

  • Not undergoing CSF or blood sampling as part of clinical practice.
  • Not undergoing cognitive testing as part of clinical practice

FOLLOW-UP

Repeated blood sampling is performed at the subsequent clinical diagnosis visit approximately 1-3 months after the initial CSF/blood collection.

Figure Dx Evaluation

Evaluation by blinded physician of diagnosis and management flowchart

Evaluation by blinded physician of diagnosis and management flowchart

Figure Clinical practice

Plasma analysis in clinical practice flowchart

Plasma analysis in clinical practice flowchart